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Discrepancies identified during the screening, full-text, and data extraction process were resolved through consensus

Signs of intradermal injection include a visible blister or raised welt at the injection site, significant stinging or burning during injection, poor absorption leading to reduced effectiveness, and visible leaking of medication from the injection site

To simplify this for dosing with an insulin syringe (which measures in units, where 100 units = 1mL): Total Volume = 2mL = 200 units

Most GI symptoms occurred during dose escalation and resolved within 4 to 8 weeks

Unlike dietary supplements, injections bypass the digestive system for immediate absorption and faster results