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10.1016/j.atherosclerosis.2010.04.024 Atherosclerosis 23 CampbellJ
However, issues included the use of toxic cyanide-containing substances, the high cost of resolving agents and catalysts, the challenge of utilizing the other enantiomer from the resolution, numerous reaction steps, low yield, high cost, and high product price
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Although GIPR agonists do not require GLP-1R to decrease body weight (179, 184), GIPR agonism was recently shown to attenuate the emetic effects of GLP-1R agonism in mice, rats and musk shrews (188)
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