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By synthesizing the role of ferroptosis in CHD pathophysiology and identifying potential therapeutic targets, we seek to provide novel insights and approaches for the prevention and treatment of this prevalent cardiovascular condition

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In STEP 1-3 clinical trials, a weekly dose of 2.4 mg semaglutide resulted in a 49% reduction in C-reactive protein (CRP) levels, while a 1 mg weekly dose led to a 42% decrease, compared to placebo after 68 weeks

5a, diamide exposure markedly increased intracellular protein-GSSG adduct formation