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Clinical trials of GLP-1 medications have shown that while weight loss occurs, it includes both fat mass and some lean mass reduction, though the impact on respiratory muscle function specifically has not been well established
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Risks include: Unknown ingredients that may interact with other medications or health conditions Lack of sterility, which can lead to infections Product that does not contain any active medication Taking GLP-1s can have side effects some moderate and some more serious, such as severe vomiting and diarrhea, severe constipation, gallstones, and pancreatitis
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Conclusions In this emulated target trial of nationwide patients with T2D and MASLD, GLP-1RA use, when compared with DPP-4i, was associated with a significantly lower risk of liver and non-liver complications
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