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The enlarged Tregs oppose the function of antigen-presenting cells (APCs), obstruct the activation of T cells, and reduce the anticancer capabilities of effector T cells (Teff) during the course of tumor development [76]
The authors reported that these effects were associated with reduced apoptosis during the in vitro aging window and suggested that Epitalon may delay oocyte aging through modulation of mitochondrial activity and oxidative stress
Generally not recommended
The most common adverse effects are mild gastrointestinal symptoms (nausea, vomiting, diarrhea) that typically occur at rates similar to placebo in controlled trials
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