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Because semaglutide is a large peptide with no structural resemblance to any screened substance, the antibodies in standard immunoassay panels will not interact with it
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The DAC version (Drug Affinity Complex) binds to albumin in the blood and stays active for roughly 68 days
[1] Its Phase 3 evidence, by contrast, belongs to the fixed combination with semaglutide marketed in trials as CagriSema where any effect cannot be attributed to cagrilintide alone
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