GLP-1 Drugs and Diabetic Eye Disease: What Patients Need to Know Quick Answer: GLP-1 drugs such as semaglutide can be very effective for type 2 diabetes and weight loss, but some studies and drug labels show a risk of temporary worsening of diabetic retinopathy, especially in people with existing eye disease and rapid glucose improvement
This limitation has direct clinical implications, as treatment decisions frequently involve dose escalation or switching between agents in the absence of head-to-head evidence
A single weigh-in can be misleading
Pharmacotherapy, including the GLP-1 receptor agonists, have also revolutionized obesity management. With limited head-to-head comparisons between bariatric surgery, bariatric endoscopy and GLP-1RAs, Velji-Ibrahim and colleagues conducted a systematic review and network meta-analysis to contrast the efficacy and safety of the three options
To make up for any nutrient gaps, you can add one or two small, nutrient-dense snacks when your appetite allows for it