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Wightman, A
During the transition: Monitor blood glucose more frequently for the first 4 to 6 weeks Expect potential hypoglycemia risk if also taking insulin or sulfonylureas Your provider may need to adjust other diabetes medications A1C improvements may be more pronounced with tirzepatide The SURPASS clinical trials demonstrated that tirzepatide 15 mg reduced A1C by up to 2.58%, compared to semaglutide 1 mg which reduced A1C by 1.86%
Options may include pursuing an exception pathway (if available), employer benefits advocacy (for employer coverage), exploring manufacturer savings programs (if eligible), or cash-pay/direct-pay programs
In terms of patients diagnosed with idiopathic generalized epilepsy or unclassifiable seizures, VPA remains also the candidate while lamotrigine and topiramate should not be considered in these patients due to lower efficacy and intolerable profiles [158]
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