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Understanding how GLP-1 works in the brain has become increasingly relevant as GLP-1 receptor agonist medicationslicensed in the UK for type 2 diabetes and weight managementproduce neurological effects including appetite suppression and potential neuroprotective benefits
When administered under medical supervision, B12 injections are well-tolerated, safe, and have minimal risk of side effects
Several studies report alterations in peripheral plasma concentrations of GSH and GSH related enzymes, however research suggests central GSH dysfunction differs from peripheral dysfunction (62)
That glucose dependence is what made the peptide interesting as a target and is why the class is described as incretin rather than insulinotropic without qualification
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