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Additionally, ferroptosis also causes the inhibition of oxidoreductases, particularly glutathione peroxidase 4 (GPX4), a lipid peroxide scavenger (Icli et al., 2019)
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The key secondary endpoints demonstrated significant reductions in atherogenic lipid levels and liver stiffness over 52 weeks in the 80 mg and 100 mg resmetirom
Their combined action ensures continuous support against oxidative stress
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