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When a blood vessel gets hurt, platelets gather to form a plug

Low counts can result from several causes such as: Side effects of certain medications you may be taking like, for instance, aspirin, ibuprofen, ampicillin, and naproxen Kidney disease Cancer of the bone marrow where platelets are created Infections like hepatitis C, HIV, and sepsis Pregnancy Abnormal immune system that attacks the platelets Heavy intake of alcohol Anemia Clotting inside the body because of which too many platelets are used up To increase blood platelets, your medical practitioner will conduct tests to identify the cause of the low counts

"Mary Shorb Lecture in Nutrition"

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This reaction has two metabolic consequences: it consumes SAM (the body's universal methyl donor) and it diverts nicotinamide away from the NAD+ salvage pathway