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FEBS Lett
intro Tirzepatide is a dual GIP and GLP-1 receptor agonist manufactured by Eli Lilly, available under two brand names: Zepbound (FDA-approved for chronic weight management and obstructive sleep apnea) and Mounjaro (FDA-approved for type 2 diabetes)
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In general, but not necessarily, the homozygous variant, often the minor allele, may confer to the affected individual a higher susceptibility in comparison with the homozygous wild-type and heterozygous condition, particularly in the occupational context wherein the exposure to chemical and physical agents may worsen the disorder
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