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This recognition is mediated by specialized molecular sensors, including pattern recognition receptors (PRRs), activated by damage-associated molecular pattern (DAMP) molecules produced upon exogenous threats and endogenous danger signals, subsequently activating inflammatory cascades [141, 142]

The silky formula is clinically proven to help strengthen the natural skin barrier, which ideal for dry and dehydrated skin types

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The wild-type (WT) or mutant GIPR was transiently transfected using Lipofectamine 2000 transfection reagent as previous described 21