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Similarly, SOD WT misfolds and develops a similar conformation to mutant SOD1, leading to aggregation and the gain of toxic functions in vitro (Bosco et al., 2010
Carl and Gerty Cori: a collaboration that changed the face of biochemistry
Typical neuropathological features of AD include the deposition of beta-amyloid (A) into neuroinflammatory plaques, intracellular aggregates of Tau protein in neurofibrillary tangles, synaptic loss, neuroinflammation, and neuronal death
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