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The off-period is intended to keep the GH receptor responsive

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Disorders of Branched-Chain Amino Acid Metabolism Maple Syrup Urine Disease Maple syrup urine disease (MSUD) is caused by deficient activity of the branched-chain ketoacid dehydrogenase complex, blocking the metabolism of branched-chain keto acids (BCKA) and amino acids (BCAA)

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