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GLP-1s offer significant benefits for many individuals living with type 2 diabetes and obesity

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Pregnant or breastfeeding women also should not use them

This study adds objective task performance and a randomized THC challenge to that picture.That is a meaningful methodological step forward, even though it does not resolve the underlying uncertainty about mechanism or long-term safety.Lens takeawayA more rigorous test of an old clinical observation, not a new consensus.Ask About Cognition SpecificallyIn practice, this study supports asking bipolar patients who use cannabis specifically about attention, sense of time, and concentration, alongside the standard mood, sleep, and substance-use review.It does not support initiating or continuing cannabis use as a cognitive intervention, given the unresolved mood and psychosis risk in this population.Lens takeawayAdd a targeted cognitive question to the visit