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Ozempic and Wegovy (and Rybelsus, which is oral semaglutide) are GLP-1 receptor agonists (glucagon-like peptide-1 receptor agonists, commonly referred to as GLP-1s) and are the only FDA-approved drugs that contain the active ingredient semaglutide
FDA.gov (2026) 10
Trinh H, Donovan A, McAdam-Marx C
Most users notice initial improvements in skin hydration and texture within 2 to 4 weeks
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