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Normal values vary based on age and sex: Ages 0-10: 14-495 ng/mL Ages 11-17: 17-633 ng/mL Ages 18-55: 37-245 ng/mL Ages 55+: 25-232 ng/mL Summary: Doctors typically check IGF-1 status when they suspect growth abnormalities, pituitary dysfunction or malnutrition
K-means clustering of amplicon sequence variant data confirmed that 5-Amino-1MQ treatment generated a distinct cecal microbiome profile from all other treatment groups including diet-switched vehicle controls indicating that NNMT inhibition produces microbiome changes that are separable from those produced by dietary composition alone
The investigators assessed body-weight change, food intake, resting energy expenditure, fat oxidation, glucose oxidation, plasma glucose, insulin, and plasma glycerol
