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Rossignol S, Drew T, Brustein E, Jiang W
In murine studies, deletion of the IGF-1R in skeletal muscle resulted in glucose intolerance issues ultimately leading to T2D at an early age, because, although they express insulin receptors, they cannot form hybrid or IGF-1 receptors [162]
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Garvey WT, Mechanick JI, Brett EM, et al