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For patients experiencing sensory peripheral neuropathy associated with metabolic diseases or medications, an initial high dose of neurotropic B vitamins (B 1 , B 6 , and B 12 ) may offer relief, followed by a transition to a lower maintenance dose upon symptom improvement [55]
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In general, the higher the EGRac, the less endogenous FAD is available, thus the poorer the blood riboflavin levels 22
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