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Structural Significance of Non-Proteinogenic Residues: Aib (N-terminal position):Reduces conformational flexibility of the peptide backbone, locking it into a bioactive conformation and enhancing its stability against enzymatic degradation D-2-Naphthylalanine (position 3):Provides hydrophobic interactions with the GHSR-1a receptor binding pocket while conferring resistance to peptidase cleavage

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This is particularly important for those taking SGLT2 inhibitors

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BME, WM, MSM, PC, BO, RL and CG: Participated in the recovery of blood samples and carried out the biochemistry determinations

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