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That's the key difference between patches and oral supplements youd ingest, such as in pill or powder form, says Charlie Seltzer, MD, a weight loss physician and exercise physiologist based in Philadelphia

Notably, the downregulation of synaptic genes aligns with literature showing age-related epigenetic changes as key factors affecting synaptic structure and function during aging (Azpurua and Eaton, 2015)

Indirect factors such as weight loss, hormonal fluctuations, dietary changes, and hydration status may influence skin health during treatment

Singh S, Pathak N, Fatima E, Negi AS