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Less frequently reported adverse reactions (less than 1% or less than twice rate of placebo) included abdominal pain upper, dry mouth, weight decreased, dizziness, somnolence, logorrhea, chest pain, anger and hypertension

The search strategy was developed according to the populations-interventions-comparators-outcome (PICO) criteria and included key and MESH terms related to MASLD patients, GLP-1 RAs, the placebo or standard of care of MASLD and the efficacy and safety of GLP-1RAs

Musculoskeletal improvements in strength, range of motion, and pain reduction typically follow over weeks 3 through 6

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