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The assessment of ototoxicity is necessary for medications delivered via the otic route that are anticipated to affect the middle or inner ear during clinical application (Pasdelou et al

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Optimized the bilayer flexibility to allow vesicles to squeeze through skin pores 1/10th their size

However, over time, if not sealed properly, it can absorb dust, bacteria, or chemicals from the air, potentially affecting its quality

It is also possible that increases in luciferase activity reflect stabilization of luciferase protein and/or enhanced luciferase translation