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If a patient follows a clinician-recommended titration and uses dietary and hydration strategies, symptoms commonly lessen within 26 weeks
According to the most recent treatment guidelines, GLP-1 agonists may be most appropriate for people with type 2 diabetes who are at a high risk for heart disease or who already have heart disease
Within this incretin-dominant environment, glucagon receptor activation may contribute more strongly to energy expenditure, fatty acid oxidation, and hepatic lipid metabolism than to uncontrolled hyperglycemia
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