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The manufacturer recommends that patients using oral hormonal contraceptives switch to a non-oral contraceptive method, or add a barrier method of contraception for 4 weeks after tirzepatide initiation and for 4 weeks after each dose escalation

These labs allow detection of pre-existing contraindications (impaired kidney or liver function, subclinical thyroid dysfunction) and provide reference values for interval monitoring during the protocol

This is based on strong clinical trial evidence they are effective

Case example : A patient receives endometrial biopsy without cervical dilation

Safety outcomes showed no significant difference between SGLT2i and placebo in nasopharyngitis, diarrhea, or hypoglycemia, albeit with a borderline increased risk of urinary tract infections