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Figure 3 Moreover, increased systematic translocation of intestinal metabolites, bacterial particulates, or even microbiota through the damaged intestinal tract (the leaky gut) heightens systemic inflammatory reactions such as Th17/Treg disorder, interleukin-6, IL-1, and tumor necrosis factors alpha that are being implicated in the etiology of depression

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Annals of the Rheumatic Diseases, 76(9), 15371543

296 : H470H479

A dynamic balance is maintained between the synthesis, consumption, and transport of GSH, all of which determine its intracellular concentration