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As a result, insulin assists cancer cells to possess a relatively higher glucose up-taking efficiency than normal cells, which may help cancer cells gain advantages in survival competitions

Gradual titration and excipient control may influence whether stabilization therapy is tolerated long enough to evaluate efficacy

Furthermore, viral protein nsp5 and nsp14 interact with host redox-enzymes: glutathione peroxidase (GPx) and peroxiredoxin (Prx), in both cytoplasm and mitochondria to dysregulate redox balance in different cellular compartments and enhance SARS-CoV-2 infection 21