Another trial, SOUL (NCT03914326), has now been initiated to overcome the shortcomings of PIONEER 6 with a primary endpoint focused at proving CV superiority vs placebo
But its too soon to say how effective it might be, and any new uses would require separate FDA approval once the studies are complete
DR OZ LINKS OBESITY TO CHRONIC DISEASE SURGE, SAYS GLP-1S CAN 'JUMPSTART' BETTER HEALTH In addition to mitigating some of the inflammation related to obesity and diabetes, GLP-1 medications have been linked to other protective effects
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In the literature, there appear to be ten other cases of colonic ischemia associated with GLP-1 agonist or GLP-1/GIP dual agonist use (Table 3) [12,13,14,15,16,17,18,19,20,21]