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Freezing compromises the molecule

However, symptoms that worsen progressively, spread beyond the immediate injection area, or are accompanied by systemic symptoms such as fever or malaise warrant prompt medical evaluation

In the body, GLP-1 acts as a multifunctional hormone with three main effects: Central appetite regulation: GLP-1 receptors in the brains appetite centres signal satiety, helping individuals feel full sooner and reducing cravings

10.2337/dc16-1324 39 De VadderF.Kovatcheva-DatcharyP.GoncalvesD.VineraJ.ZitounC.DuchamptA.et al (2014)