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The scientific community, however, holds reservations regarding their efficacy against Borrelia burgdorferi

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Giannoulis MG, Sonksen PH, Umpleby M, et al

Patients should also be aware of potential side effects, which may include local irritation or allergic reactions, although these are generally rare

Well-designed randomized clinical studies are needed to systematically evaluate the evidence for the use of these hepatoprotective agents as treatment options for APAP-induced liver injury, to determine the timing of initiation of the therapy, and to further define the optimal treatment regimen