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The STEP trials purposely excluded individuals with a history of major depressive disorder (MDD), bipolar disorder, schizophrenia, or other significant mental illnesses as well as participants with past suicide attempts or who had experienced clinically significant suicidal thoughts
In participants with overweight/obesity without diabetes, the highest dose of retatrutide produced 24.2% reduction in body weight after 48 weeks [75]
Cancer 22 FloreanC.SchnekenburgerM.GrandjenetteC.DicatoM.DiederichM
Any changes in liver-related symptoms or new abnormalities in home monitoring (such as unexplained weight gain suggesting fluid retention) should prompt earlier review
One of the most popular GLP-1 receptor agonists is Ozempic, a semaglutide medication that's technically designed to help control blood sugar in people with type 2 diabetes
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