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Body Protective Compound 157 (BPC-157) is a peptide that has garnered recent attention for its ability to exert systemic effects on both the brain and the gut, thereby aiding in their repair

In: Moliterno Gunel J, Piepmeier JM, Baehring JM (eds) Malignant brain tumors: state-of-the-art treatment

Used as a research chemical to investigate this peptide in experimental models

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(2015), BioMed Research International 2015:648108, PubMed 26236730 Statistics from research literature Discovered by Loren Pickart in human blood plasma in 1973 , as a factor extending the longevity of cultured liver cells The smallest peptide with documented pharmacological activity: 3 amino acids (Gly-His-Lys) + one Cu ion Molecular weight: 402 Da EU cosmetic INCI name: Copper Tripeptide-1 (registered in EU Commission CosIng database) Gene expression modulation: 4 000 human genes (Connectivity Map dataset, Pickart 2015) Plasma level in healthy humans declines from ~200 ng/mL at age 20 to ~80 ng/mL at age 60 (62 % decrease) Most-studied bioactivities: fibroblast proliferation , type I/III collagen synthesis , antioxidant activity (SOD upregulation) Reference sources (PubMed) Pickart L., Vasquez-Soltero JM., Margolina A