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However, development was discontinued in 2007 after the largest Phase IIb trial failed to demonstrate statistically significant weight loss compared to placebo
Research has examined investigated effects on adipocyte differentiation markers, browning markers (the conversion of white adipose toward brown-like phenotype), and broader adipocyte biology
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[50] [51] [52] [53] Diagnosis [edit] The insidious nature of PA may mean that diagnosis is delayed
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