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Unlike other polyphenols, curcumin simultaneously inhibits NOX4-mediated superoxide burst and up-regulates NGF, providing a dual antioxidant-neurotrophic axis unique among plant polyphenols (Zhao et al., 2014
Glutathione peroxidases at work on epididymal spermatozoa: an example of the dual effect of reactive oxygen species on mammalian male fertilizing ability
Ans : Slightly, with long-term use
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These tools enable real-time visualization of receptor binding and activation, trafficking, and ligand-receptor dynamics in living cells and tissues , dramatically improving the reliability and throughput of drug screening
