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Mechanistically, alterations in gut microbial metabolites such as SCFAs could affect the integrity of the BBB, induce systemic endotoxemia, and activate microglia so as to impact disease progression

The sensor showed an excellent detection of ions, and cytotoxicity study showed that Cu (II) and Zn (II) complexes, had acquired an anti-cancer effect through the induction of phenotypic changes and membrane permeability improvement which were constant with the cell death induction due to apoptosis [143]

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