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-MSH is a neuropeptide belonging to melanocortin family, and plays important role in stimulating melanogenesis as well as production of eumelanin, the pigment for skin and hair color
For context, headache rates with tirzepatide and semaglutide are similar or slightly higher, suggesting this is more of a general weight-loss medication effect than something specific to cagrilintide pharmacology
Lets look at two clear examples in this study of how refined carbohydrate intake was completely ignored by the authors
Increasing the intake of nutrients such as fiber, protein and exercise will do exactly the same while feeding your gut microbiome, stabilizing your hormones and blood sugar and mental health, while increasing your muscle mass naturally
This supports a model in which CHAC1-mediated GSH depletion destabilizes NRF2 and reduces cystine import, allowing iron-dependent lipid peroxides to accumulate and trigger ferroptosis
