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When to reassess If GI symptoms worsen instead of improving over the first 2-3 weeks of a step, if you cannot keep food down, or if you have severe persistent abdominal pain (especially with back radiation), pause and consult a qualified clinician

The psychological impact of rapid weight loss itself represents a significant confounding factor

Liver enzymes elevated Mild elevations (1-2x upper normal) during the first month are common and typically self-resolve

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Applications in Cellular Senescence Models Cellular senescence is the foundation of organismal aging