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Now used for obesity treatment without diabetes, GLP-1 receptor agonists are available in various forms, including injectable options like exenatide extended-release

(A placebo is a treatment with no active drug.) People in this study had type 2 diabetes

Exercise With exercise, the ultimate goal is to move up to weighted squats, lunges, and deadlifts

These trials test retatrutide for obesity, type 2 diabetes, cardiovascular disease, knee osteoarthritis, and liver disease (Giblin et al., Diabetes, Obesity and Metabolism 2026)