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Symptoms of a serious allergic reaction (anaphylaxis) include: Difficulty breathing or wheezing Swelling of the face, lips, or tongue A feeling of tightness or pressure in the chest Rapid heartbeat and dizziness Kidney Stress and Dehydration Severe nausea and vomiting can lead to dehydration, which places stress on the kidneys

These effects were magnified in combination therapy protocols , with some studies noting weight reductions of up to 15% when paired with semaglutide

How Tirzepatide Works Tirzepatide works in a similar way but with an additional mechanism that targets more than one metabolic hormone

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