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Secondary hypertension is usually associated with an earlier age of onset, no family history, and a clear cause, such as renal or endocrine disorders, or iatrogenic triggers, such as the use of oral contraceptives (131)

This is especially relevant during the first two months of treatment

Kisspeptin increases GnRH, which increases FSH and LH, promoting follicle development and sperm production

Rather than directly suppressing inflammation or repairing tissue, it works at the level of immune system regulation, promoting the development and function of regulatory T cells that keep autoimmune responses in check