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Its a highly abundant small protein naturally found inside human cells and circulating throughout the body

Cancer Res 54 : 22182222 Resnicoff M, Tjuvajev J, Rotman HL, Abraham D, Curtis M, Aiken R, Baserga R (1996) Regression of C6 rat brain tumors by cells expressing an antisense insulin-like growth factor I receptor RNA

After the surgery the animals were maintained under a 12 hour light/12 hour dark cycle and were closely monitored and gently handled for 5 minutes per day, 5-6 days after the surgery was performed [2]

The analysis of SOD activity revealed variable responses depending on the brain region and treatment applied