Measurement of Homocysteine written by Dr Gillian Hart BSc (Hons), PhD, Cert Mgmt (Open), MIBMS The importance of homocysteine as a risk factor is becoming much more familiar as evidence grows
NICE guidance recommends intramuscular hydroxocobalamin as first-line treatment for B12 deficiency caused by pernicious anaemia or malabsorption
The procedure is brief and minimally uncomfortable
Our results indicate glutathione depletion upon treatment with AITC, corroborating earlier studies 17,40,75
Results clearly showed that the tyrosine-nitration level was reduced in proportion to the molar ratios of GSSSG and LASSS relative to HGF, as revealed by the decrease in anti-nitroY mAb-positive HGF (60-kDa -chain and 90-kDa proform) normalized to total HGF -chain as a loading control, that was monitored by stripping with SDS-ME solution and re-probing the blot with anti-HGF -chain N-terminal domain mAb (Figure 1b,c, second and third rows)