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Small for gestational age: short stature and beyond
Gastrointestinal AEs were the most frequently observed AEs, consistent with previous findings [5, 10,11,12,13,14,15,16,17,18]
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The biotransformation occurs at the level of CoA derivatives [22, 23], while the initially described CDH and CR activities were shown to depend on two proteins (enoyl-CoA hydratase, CaiD, EC 4.2.1.89, and crotonobetainyl-CoA reductase, CaiA, EC 1.3.99, respectively) both needing the joint action of a transferase (crotonobetainyl-CoA:carnitine CoA transferase, CaiB, EC 2.8.3) to allow the CoA-cycling between products and substrates of the biotransformation [24, 25]
doi: 10.1002/1097-0142(19810501)47:9 3.0.CO;2-6 9 WiviottSDRazIBonacaMPMosenzonOKatoETCahnAet al
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