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Tirzepatide liver-fat and body-composition MRI substudy SURPASS-3, relative liver-fat reduction -29.8/-39.6/-47.1% at 5/10/15 mg vs insulin degludec -11.2%: Gastaldelli Lancet D&E 2022
Kim D, Kiprov DD, Luellen C, et al
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Tesamorelin GH/IGF-1 Axis Stimulation Tesamorelins mechanism runs through the opposite route: it signals the pituitary gland to increase natural growth hormone production, which in turn raises IGF-1 levels and drives fat metabolism as a downstream effect of that broader hormonal cascade
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