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This remarkable therapeutic window suggests low potential for dose-related toxicity and flexibility in clinical dosing

However, -tocopherol supplementation did not affect scores on the Alzheimers Disease Assessment Scale and the Mini-Mental State Examination, which in part involve assessment of memory performance (122)

Future perspectives and outstanding questions Despite substantial progress, several unmet needs and key questions require investigation to fully realize the therapeutic potential of GLP-1-based therapies in MASLD/MASH

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Specific examples of executive functions include shifting between two behaviors, inhibiting habitual behaviors, updating information, and planning (131)