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First, let me caution that this is just a mouse study, so it may not hold true in humans
If the 4 mg maintenance arm proves non-inferior for weight maintenance in Phase 3, researchers may be able to titrate up to a high working dose during the active weight-loss phase, then step back down to a lower 4 mg maintenance dose for the long stabilization phase
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It pushes it underground, where there's no pharmacist, no quality standard, and no way to build the very evidence everyone agrees is missing
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