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Staying hydrated is especially important, as both treatments can contribute to mild dehydration

The compound emerged from Lillys programme to extend the pharmacological scope of dual GLP-1R/GIPR agonists (exemplified by tirzepatide) by incorporating GCGR agonism, which adds a third, complementary mechanism relevant to hepatic glucose output and thermogenic energy expenditure

Jia G, Aroor AR, Sowers JR

Semaglutide is not a restriction medication, but your body becomes more sensitive to fatty, sugary, and hard-to-digest foods as your stomach empties more slowly

Limit intake to 200 to 300 mg daily (about 2 to 3 cups of coffee) and cut off caffeine by 2 PM