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NAD precursors (nicotinamide riboside, nicotinamide mononucleotide) work by directly supplying building blocks for NAD synthesis

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This does not invalidate the findings, but it means the evidence base is not yet at the level of FDA-approved pharmaceuticals

That process requires cell membranes that stay structurally intact, mitochondria that produce energy efficiently, and antioxidant systems that clear damage before it compounds

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