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Although high treatment cost remains a major barrier, adherence patterns require further investigation to inform strategies that improve long-term persistence

Insurance coverage, supply dynamics and socioeconomic disparities also play a major role in the discontinuation patterns, as demonstrated by our findings that individuals with Medicare or Medicaid switched agents more often compared to their counterparts with commercial insurance coverage [37,38]

Others experience reduced appetite post-meal, facilitating easier snacking elimination or portion control

Large, heavy meals

Weeks 8-12: Full results, including a deeper, longer-lasting tan, improved UV protection, and stable weight management